This chapter explores such topics as innovation, the most innovative colleges and companies, America’s innovation strategy, problem-solving strategies, DARPA (Defense Advanced Research Projects Agency), the eight disciplines from the Ford Motor Company, military design thinking, appreciative inquiry, grounded theory, morphological analysis, the 2 × 2 matrix, synectics, problem-solving and re-engineering, cost-effectiveness, the Leontief Model, clock speed, and the George Washington University class curriculum on thinking.