ABSTRACT
One of the fundamental requirements of the herbal industry is the identification and quality evaluation of crude herbs and products. The genus Terminalia is a rich source of tannins. This chapter investigates the effect of geographic location on the distribution of phytoconstituents in T. chebula fruits collected from three different locations in three consecutive years by simultaneously determining the quantitative contents of 17 bioactive phytoconstituents using UPLC-QqQLIT-MS. The proposed UPLC-ESI-MS/MS method for quantitative analysis was validated according to the ICH, Q2R1 guidelines by determining calibration curves, lower limit of detection (LOD), lower limit of quantification (LOQ), specificity, precision, solution stability and recovery. Comprehensive estimation of selected bioactive compounds could make a contribution to the quality control of T. chebula species and its herbal formulations.
