ABSTRACT
The incidence of prostatic leiomyoma is high if small stromal nodules encountered in benign nodular hyperplasia (BNH) are counted as tumors. The tumor may contain moderate amounts of fibrocollagenous tissue, but is completely devoid of epithelial elements. The occurrence of leiomyoma with atypical nuclear changes is not uncommon in the uterus. Microscopically, the tumor is composed of interlacing bundles of smooth muscle cells. Areas with increased cellularity alternate with hypocellular areas. Scattered among the fusiform smooth muscle cells are peculiar, bizarre, giant cells. The spindle cells were surrounded by incompletely formed basal lamina and contained myofilaments with dense bodies. The nuclei were basophilic and had a wavy configuration and pointed ends. The tumor is composed of large polygonal cells with distinct cell membranes. The individual cells have small, centrally placed, dark nuclei and a coarsely granular eosinophilic cytoplasm.
