ABSTRACT
For decades, catalysis has remained an indispensable agent of quick positive transformation for life and society. The goal of catalysis is the effective optimisation of resources to meet some immediate and future needs. Catalysis is the main driving force for key sectors of the global economy, such as petroleum and energy production, chemicals and polymer manufacturing, the food industry and pollution control. Homogenous catalysis is the type of catalysis in which the catalyst is in the same phase (physical state) as the reactant. In heterogeneous catalysis, the catalyst and the reactant are in different physical states (phases). Vitamin B12, also known as cobalamin (Cbl), is a versatile natural organometallic complex of interesting catalytic properties. The stability of the Cbl family, particularly the vitamin B12 coenzymes, is due to the unprecedented degree of stability of their organometallic Co-C bond, in addition to the central Co-atom obeying the general 18-valence electron rule when the derivatives are in their free state.
