ABSTRACT
Clinical studies that included large number of patients representing both early and late stages of the epidemic have shown both changing and constant patterns of different clinical and socio-demographic features. Such trends have also been observed within the broad clinical profile of cutaneous leishmaniasis that continued to remain otherwise undisturbed. Increasing involvement of females and older age groups had been observed. Spatial distribution of cases of cutaneous leishmaniasis had expanded over time. Seasonal variation of case presentation with two peaks each year had been observed since long. Atypical manifestations associated with cutaneous leishmaniasis in Sri Lanka were identified to behave differently, and this category was recently described as a clinical entity different from classical cutaneous leishmaniasis in Sri Lanka. Long-term existence of two independent disease transmission foci with different clinical and socio-demographic profiles in Northern and Southern Sri Lanka had been reported. A subsequent analysis revealed different patterns in progression of classical cutaneous infections in the two areas.
