ABSTRACT
This chapter discusses Mammal Models and Humans. Mammalian models, primarily rodents like mice and rats, play a pivotal role in scientific research by contributing significantly to our understanding of various biological processes and human health. They are essential for evaluating the safety and toxicity of drugs, chemicals, and environmental agents, helping assess potential adverse effects on organs, systems, and overall health. In the context of TiO2 nanoparticles (NPs), numerous mammalian models, both in vivo and in vitro, have been employed to investigate their mechanisms of action and potential toxicity to humans. These studies collectively provide valuable insights into the potential adverse effects and mechanisms of TiO2 NPs in mammalian models, contributing to our understanding of their impact on human health.
