ABSTRACT
The integument comprises the skin, which can be considered the largest organ of the body, and its derivatives. In this chapter, we describe thoroughly the different layers of the skin: the epidermis, the dermis, and the subcutis. The sebaceous, sweat, and highly specialised mammary glands, together with the histology and the development of hairs and hair follicles, claws, horns, or hooves, are also described. The skin and its appendages differ dramatically in non-mammalian animal species, and special features like feathers in avian species, scales in reptiles, or toxin-producing skin glands in amphibians are described as well as different clinical cases in a variety of species.
