ABSTRACT
In this region, soft-tissue fillers usually are the first-line choice, rather than botulinum toxin, to provide structure and support. However, botulinum toxin can be considered for the treatment of dynamic lines, projection of the mentum, the mental crease, the position of the oral commissures, as well as for the treatment of hypertrophic masseter muscles which can lead to facial shape remodeling. A possible second injection site is at the mandibular border. The injections are located 1-3 mm from the midline at a depth of approximately 4-9 mm to prevent diffusion to the laterallyancl more superficially-located DLL The cranial area of the muscle does require treatment to reduce the risk of spread to the orbicularis oris muscle. Injection pattern for chin dimples and horizontal sulcus. The cranial limit of the treatment area is an imaginary line from the earlobe to the oral commissure. The muscle strength decreases in 2 weeks, but the improvement in contour will take longer.
