Powders and granules
DOI link for Powders and granules
Powders and granules book
This chapter discusses desired quality attributes of powders and granules and techniques for their quantitation. It describes methods of production of granules and methods of production of amorphous powders. Uniform distribution of each component in a powder mixture is desired to assure uniform subdivision of the individual components when the powder mixture is subdivided. The powders used in pharmaceutical industry and pharmacy practice could be either crystalline or amorphous in nature. Crystallization is the production of solid crystals in a solution of the solute being crystallized, which is followed by the subsequent separation of those crystals from the solution. Polymorphism refers to the ability of a solid to exist in more than one crystal structure or form. Intrinsic properties of a molecule together with crystallization conditions determine the possibility of existence of different crystalline or amorphous forms of a molecule.