ABSTRACT

This chapter illustrates the analyses of longitudinal clinical trial data using the principles and recommendations outlined in previous chapters. The analyses conducted here are for illustration and should not be considered universal recommendations for similar situations. Data for these analyses are the so-called high and low dropout (large) data sets described in Chapter 4. Recall, these data are somewhat contrived for convenience, but were extracted from two real clinical trials and thus provide a useful illustration of analyses, model verification procedures, and sensitivity analyses. Parts of this example were previously reported in Molenberghs et al. (2015, chapter 22).