ABSTRACT
The generalized approach suffers, naturally, from appearing to be a little more removed from concrete cases, but it renders an important service in being immediately applicable to a large number of real chromatographic problems. The generalized nonequilibrium theory may then be applied to the model in order to derive a plate height expression. As pointed out earlier, the rigorous nonequilibrium approach has a real advantage over approximate theories such as that based on the random walk. The nonequilibrium theory of transparticle diffusion is relatively simple because the velocity of the mobile phase is uniformly zero. In striving to mold the nonequilibrium theory to real chromatographic systems, people must proceed considerably beyond the simple mass transfer mechanisms. The generalized nonequilibrium theory is not a total and complete theory of the dynamics of chromatography. The generalized nonequilibrium theory can be extended to the non linear sorption of solutes.
