SEDIMENTATION velocity (SV) analysis is concerned with the interpretationof the temporal evolution of the radial concentration gradients of particles in solution under the influence of a centrifugal field. This is distinct in theory and practice from the thermodynamic analysis of the final equilibrium state, which is subject to sedimentation equilibrium (SE) analysis. Both are different flavors of analytical ultracentrifugation (AUC), a technique to monitor macromolecular sedimentation in solution in real time [1].