ABSTRACT

One of the few liquid chromatographic techniques that can be predictably scaled up from an analytical to production scale is countercurrent chromatography (CCC) (Wood et al., 2007). CCC is a descriptive term for continuous liquid-liquid partition processes that do not employ any solid supporting matrix. Liquid-liquid partitioning

8.1 Introduction .................................................................................................. 261 8.2 Enrichment and Prefractionation of Crude Phenolic Extracts

Prior to CCC ............................................................................................ 262 8.2.1 The Use of Polyamide and Polyvinylpolypyrrolidone ...................... 263

8.2.1.1 Basic Principles .................................................................. 263 8.2.1.2 Mechanistic Studies ...........................................................264 8.2.1.3 Selected Applications .........................................................264