ABSTRACT

Fluoride is probably the rst inorganic ion that drew attention of scientic world for its toxic effects on development, and now the uoride toxicity through drinking water is well recognized as a global health problem. World Health Organization (WHO, 2010) recommended an optimal level of uoride in drinking water, for the prevention of dental caries and normal growth of dentition. When uoride in drinking water is added under uoridation program in many countries, and also through other dietary sources, foodstuffs, and beverages, the optimal daily uptake for individuals is often exceeded. This results in uncontrolled and unpredictable consumption of uoride that may often exceed its therapeutic value, thereby inducing negative health impacts within the population as a whole. Fluoride efciency and deciency exert an inimical impact on the sustainability of the organism (Mohapatra et al., 2009).