ABSTRACT
Drug delivery is a eld of vital importance to medicine and healthcare. Controlled drug delivery improves bioavailability by preventing premature degradation and enhancing uptake, maintains drug concentration within the therapeutic window by controlling the drug release rate, and reduces side effects by targeting disease site and target cells. Since the rst FDA approval of DDS, Liposomal amphotericin B, in 1990, more than 10 DDS are now commercially available to treat diverse diseases ranging from cancer to fungal infection and to muscular degeneration (Figure 4.1 and Table 4.1) [2].
