Biomaterials can be dened as any nonviable synthetic materials that become a part of the body either temporarily or permanently to replace, augment, or restore the function of a body tissue and are continuously or intermittently in contact with body uids in a safe, reliably economically, and physiologically acceptable manner; they can be used for any period of time in contact with living tissue, to improve human health and they play a central role in extracorporeal devices, from contact lenses to kidney dialyzers, and are essential components of implants, from vascular grafts to cardiac pacemakers. A variety of devices and materials are used in the treatment of disease or injury. Common examples include suture needles, plates, teeth llings, etc. However, this denition excludes surgical or dental instruments as they are exposed to body uids, but do not replace or augment the function of a human tissue [11].