ABSTRACT

This chapter provides an overview of the application of green chemistry principles to analytical chemistry. It shows that more specific principles are useful for green analytical chemistry (GAC). The chapter provides specific examples of such a greening, which are accessible to the students of organic chemistry with some exposure to analytical chemistry. It addresses the instrument ranking based on one GAC criterion, that of energy consumption. The chapter learns that the Fourier transform infrared instrument is greener than the nuclear magnetic resonance, based on its energy consumption. It shows energy consumption ranking for selected instruments that organic chemistry students are typically familiar with, together with the numerical and color ranking for greenness. Several investigators felt that analytical chemistry is sufficiently different from other branches of chemistry that it would benefit from tailoring and supplementing the green chemistry principles to match analytical chemistry applications. Pharmaceutical industry uses chromatography for preparative separations, at all stages, including drug discovery, process development, and manufacturing.