ABSTRACT
Many organic solvents are toxic to humans and other life, and may be hazardous to the environment. Notably, many solvents are volatile organic compounds, which can easily escape to the environment. This chapter focuses on solvent less solid/solid reactions that are affected by mixing or grinding of two or more reactants, which results in the melting of the reaction mixture. The eutectic point can occur at any ratio between two compounds, which depends on their structures and melting points. It should be noted that some mixtures of compounds may show no eutectic point or a more complex behavior, in which there is more than one eutectic point. The lost positives of the solvents need to be compensated for when the solvent less reactions are put into practical use. Green solutions need to be tailored to each specific reaction or process.
