ABSTRACT
This chapter documents Dr. Maven's education in the basic principles of pesticide bioassay. She learns many lessons by trial and error; the problems that she encounters are described in the chapter. The simplest quantal response bioassay is a binary quantal response experiment with one explanatory variable. This is the kind of bioassay that Dr. Maven has Jessica do first with the laboratory colony of P. giganticus. The chapter shows the statistical statement of the binary quantal response with a single explanatory variable. In a quantal response bioassay, the points along the regression line are such that, for a given dose or concentration on the x axis, there is a corresponding probability level of response. The specific nature of hypotheses can be tested with binary quantal response bioassays. The way a particular bioassay should be done to estimate a given lethal dose (LD) or lethal concentration (LC) depends on the response level of interest.
