ABSTRACT
This chapter details what is required in terms of competencies, skills and knowledge from junior physicians in core medical training in neurology. Myotonic dystrophy is an inherited myopathy with features developing at around 20–30 years old. It affects skeletal, cardiac and smooth muscle. Oculogyric crisis is an acute dystonic reaction of the face/eyes and is usually a consequence of typical neuroleptic drugs such as haloperidol and chlorpromazine but is unusual with newer agents such as olanzapine anad clozapine. Clozapine, one of the first atypical agents to be developed, carries a significant risk of agranulocytosis, and full blood count monitoring is therefore essential during treatment. For this reason clozapine should only be used in patients resistant to other antipsychotic medication. Dementia is a clinical state characterised by loss of function in multiple cognitive domains beyond what might be expected from normal ageing. The most common form of dementia, Alzheimer's disease, accounts for 50%–75% of all cases of dementia.
