ABSTRACT

Learning objectives ■ The sympathetic division of the ANS ■ Anatomical layout of the SNS ■ Actions of the SNS on tissues and organs ■ Adrenoceptor

classifi cation ■ Current knowledge of 1-adrenoceptor subtype function ■ Current knowledge of 2-adrenoceptor subtype function ■ Release, action and

inactivation of norepinephrine ■ Biosynthesis of norepinephrine and epinephrine ■ Metabolism of epinephrine and norepinephrine (NE) ■ Therapeutic drugs acting

through the SNS

Learning objectives Be able to sketch the layout of the SNS. ■ Know the main points about SNS actions on the different systems. ■ Have knowledge of the main classifi cation subdivisions of the ■ adrenoceptors. Be able to sketch the events at the adrenergic synapse following arrival of ■ the nerve impulse. Know the pathways of synthesis and inactivation of NE and epinephrine. ■ Be able to give at least one example of a therapeutic drug and its ■ adrenoceptor site.