ABSTRACT

Targets specifi cally lysine and arginine residues at the C-terminal. ■ Digests insoluble fi brin to release soluble fi brin degradation products ■ (FDPs).*

Potentiates its own activity by promoting tPA and uPA production. ■ Activity is terminated mainly by ■ α2-antiplasmin (plasmin inhibitor) and α2-macroglobulin.