ABSTRACT
Question 1 Cytoarchitectural abnormalities have been reported in the entorhinal cortex in schizophrenia. ἀ e changes that are suggestive of disturbed development include all of the following, with the exception of a. Aberrant invaginations of the surface b. Disruption of the cortical layers c. Heterotopic displacement of neurons d. Paucity of neurons in supercial layers e. Increased density of neurons in the deeper layer
Question 2 A neurologist has been called to the emergency service to assess a 70-year-old man. It was noted that the man was unable to speak and comprehend speech. Which terminology best describes this? a. Alexia b. Agraphia c. Apraxia d. Aphasia e. Amusia
Question 3 A 22-year-old male has been started on a new medication known as quetiapine to help him with his symptoms. He has been measuring his blood pressure daily and he has noted that his blood pressure is now lower when he takes the medication. ἀ is is due to the eect of a. Blockage of the serotonin receptors b. Blockage of the alpha-1 adrenergic receptors c. Blockage of the alpha-2 adrenergic receptors d. Blockage of the dopamine-1 receptors e. Blockage of the dopamine-2 receptors
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fertilization. ἀ ey found a 2-year-old boy whom they were keen to adopt. However, they realized that the child’s biological parents were alcoholic. What is the risk ratio of the child having similar alcohol dependence? a. At least two times more b. At least three times more c. At least four times more d. At least ve times more e. At least six times more
Question 5 Based on epidemiological studies, roughly what percentage of patients with late paraphrenia would resemble that with paranoid schizophrenia? a. 10% b. 20% c. 40% d. 60% e. 80%
Question 6 ἀ e ICD-10 and the DSM-5 both have a specic constellation of symptoms for the diagnosis of borderline personality disorder. Which of the following clinical signs and symptoms would improve over time? a. Irritability b. Impulsiveness c. Aective instability d. Self-harm e. Unstable relationships
Question 7 A 6-year-old child was lost whilst he was out shopping with his mother. Initially, he showed marked signs of distress when he realized that he was lost, but when his mother returned, he began to ignore her. Based on Ainsworth’s theory, what particular type of attachment would this be? a. Secure attachment b. Anxious ambivalent c. Avoidant d. Disorganized e. Atypical
Question 8 Based on epidemiological studies, roughly what percentage of people with schizophrenia would have an onset older than 60 years? a. 0.5% b. 1.0% c. 1.5%
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Question 9 Antidepressants that act on which one of the following receptors might cause weight gain? a. Histamine b. Serotonin 5HT-1 c. Serotonin 5HT-3 d. Dopamine D1 e. Dopamine D2
Question 10 Which of the following statements about serotonin is incorrect? a. Serotonin is synthesized from dietary amino acid l -tryptophan. b. Depletion of serotonin could be achieved by inhibiting tryptophan
hydroxylase, removing l -tryptophan from the diet or adding natural amino acids such as alanine to compete for the transport process with l -tryptophan.
