ABSTRACT
Whipple disease is a rare systemic infection caused by the bacterium Tropheryma whipplei. It may aect any part of the body but is most commonly considered a gastrointestinal disease. Biopsy will reveal periodic acid-Schi (PAS)-positive macrophage inclusions. Treatment is with antibiotics for up to 2 years, and this may not be successful and result in relapse. Cryptosporidiosis is a parasitic disease which will cause selflimiting diarrhoea in those not immunocompromised. However, in the immunocompromised a more severe form may manifest.
