ABSTRACT

This blood films is from a 34-year-old woman who has a white blood cell (WBC) count of 63 × 109/L. She was initially treated with four courses of intensive chemotherapy and entered complete remission. She relapsed 6 months later, remission was again achieved with chemotherapy and she then received an allogeneic bone marrow transplant from a fully human leukocyte antigen (HLA) compatible sibling. What is the likely diagnosis at presentation? What chromosomal translocation is typically seen?