ABSTRACT
Asbestos was rst suspected of causing human lung cancer in the 1930s, when pathologists found a rare incidental neoplasm, lung cancer, among several asbestos manufacturing workers who had died from asbestosis and had undergone autopsy in the United States and England (Figure 22.1) (Gloyne, 1935; Lynch et al., 1935). Soon thereafter, industry sponsored an animal assay at the Saranac Laboratory in upstate New York and con-rmed that asbestos caused lung tumours in rodents (Castleman, 2005). The study results were suppressed, although epidemiological studies of asbestos workers were subsequently published in the 1950s, demonstrating that asbestos workers experienced excess lung cancer death rates (Doll, 1955).
