ABSTRACT

The attitude of elite chemists toward statistics has not improved much from when Rutherford made this insulting statement. Perhaps, the reason is that the standard methods for the DOE don’t work very well on mixtures. For example, let’s say you get a new ultra-high-shear blender and start tossing in various fruits to see if you can make a tasty “smoothie” drink. Table 11.1 shows the experimental layout for a fanciful concoction that might be branded “BanApple.” Is this a good design?