ABSTRACT

Routine parenteral administration by injection serves to deliver drugs to body tissues. The most important routes of injection of these sterile products are intramuscular (i.m.), intravenous (i.v.), and subcutaneous (s.c.). The process of developing conventional parenteral formulations involves the selection of appropriate vehicles (e.g., aqueous, oily, and emulsions) to achieve the desired bioavailability following injection, as described in Chapter 3. The present chapter focuses on advanced drug delivery and targeting systems (DDTS), in the nanometer range, administered via the parenteral route and serves to provide the reader with a basic understanding of the principle approaches to drug targeting.