ABSTRACT

Candidiasis is a yeast fungal infection which can affect any part of the body, particularly warm, moist areas such as the vagina, mouth and armpits. Candida is always present on the body and certain physiological factors cause the fungus to flourish and cause infection. The most common infection is Candida albicans, first described in 1923 by Christine Berkhout. Candida – also referred to as moniliasis or 'thrush' – is the most frequent cause of vaginitis. In males Candida can cause Candida balanitis and Candida balanoposthitis. In people with a compromised immune system, such as those with AIDS or receiving organ antirejection treatment, Candida can spread systemically with very serious consequences and is potentially fatal. The most commonly affected organs are the brain, eyes, heart and kidneys. Some local application creams are available in combination with hydrocortisone, also available for local application. Partners also require treatment to prevent recurrent or chronic candidiasis.