The Ramsar convention, which originated in Iran, identified the wetlands of global tropical and temperate countries from different continents that need scientific attention. Thus, descriptions of global Ramsar sites provide their current global status. Biodiversity hotspots of Myers as published in the journal Nature are conservation focus sites with immense diversity of aquatic and terrestrial plants. Nevertheless, these global biodiversity hotspot sites are rarely investigated for wetland plants and phytoremediation perspective, probably in view geographical constraints, besides other ethnolinguistic constraints. Here, we discuss the research observation in the context of wetland ecology, water quality, and emerging contaminant (metals/metalloids) analysis of a Ramsar site of environmental and economic relevance. These research investigations may assist in eco-management of this and other global wetlands inextricably linked with sustainable development. To this end, biodiversity prospecting and screening of potent wetland plants in such biodiversity-rich regions may result in an eco-technological innovation for the treatment of global emerging contaminants.