In recent decades, nanotechnology as a bullet train is running at a fast pace, with different environmental as well as human welfare applications, specifically in context of environment, bioenergy, agriculture systems, and wetland plants. Nevertheless, the rapid pace of nanorevolution aroused concerns in relation to the fate of nanoparticles (NPs) in the environment and the resulting adverse impacts on its biotic/abiotic components, specifically plants, constructed/natural wetlands, and human health impacts due to nanotoxicity. Furthermore, NP and plant interaction is inextricably linked with environment (phytosynthesis of NPs and phytoremediation of water, air, and soil), bioenergy, and agriculture systems. In this chapter, we will try to understand nanotechnology and its applications and constraints to the environment and health sector. Here, it is worth mentioning that NPs may also be treated as a recent form of emerging contaminants. To this end, plants being at interfaces of abiotic and biotic environment can be a potent tool to understand nano-ecotoxicology. Henceforth, the present chapter will attempt to analyze whether phytoremediation/phytotechnologies through applications of wetland plants will be able to address the problem of NPs as emerging contaminants.