Acute Inhalational, Oral, and Intraperitoneal Toxicity of Methyl Chloroform in Mice

Studies on experimental animals have been the basis for most of our understanding of the effects of methyl chloroform (1,1,1-trichloroethane) on man. Acute toxicity following oral,36,69 intraperitoneal,62–65 or inhalationa160,62 administration of methyl chloroform has been studied in different experimental animals. However, a comparative investigation of methyl chloroform toxicity following its administration to a single animal species via different routes has not yet been reported.