ABSTRACT

The Salmonella, like most other bacteria, are susceptible to a wide variety of chemicals which can be used to inhibit or to control the growth of the bacteria. When one considers the reactions of bacteria to chemical compounds, the organisms must be considered to be either sensitive or resistant to the agent. Generally, one considers bacteria to be resistant to a chemical if that organism does not show susceptibility which may be expected. It is recommended that antibiotics be used to treat enteric fever whenever there is bacteremia. When there is fever, vomiting, and diarrhoea in nontyphoid salmonellosis, antibiotics should not be used. In any Salmonella infection it appears that the normal gut bacterial flora plays a protective role since the alteration of that flora with antibiotic therapy seems to increase the risk of developing salmonellosis. When antibiotics are used for treatment, the specific mode of action against the pathogen is dependent on the antibiotic in use.