ABSTRACT

The consequences are most serious at the time of most rapid bone growth — in infancy; the infant with scurvy tends to lie still on its back in the frog-leg position with its legs flexed at the knees and the hips and its thighs abducted and externally rotated. K. A. L. Aschoff and W. Koch made a detailed study of the bone pathology in human scurvy, as seen in soldiers who died of the disease during the World War I. Particular attention was paid to changes in the bone and cartilage at the costochondral junctions and also at the junction of the diaphysis and the epiphysis of the long bones. Scurvy affects growing bones, so X-ray changes are seen most frequently in infants and young children and most notably at the ends of the long bones. Slipped epiphyses occur both in infants and in older children; osteoporosis and fractures have often been reported in adults with scurvy.