ABSTRACT
Nuclear Transformation ............................................................. 299 11.5 Plant Molecular Farming Versus Conventional
Bioproduction Systems .............................................................. 300 11.6 Disadvantages of Plant Molecular Farming ............................... 301 11.7 Important Transgenic Plants ....................................................... 302 11.8 Advantages Associated with Transgenic Plants ......................... 306 11.9 Conclusions ................................................................................ 309 11.10 Review Questions .................................................................... 309 Keywords .............................................................................................. 310 References ............................................................................................. 310
11.1 INTRODUCTION
Transgenic plants have emerged as a promising candidate for the production of recombinant proteins with great potential in industry and clinical prospects. This novel system offers several advantages over conventional of using conventional bioproduction systems such as bacteria, yeast, and cultured insect and animal cells. The advantages can be listed as safe system,
scale of production increases multi-fold, cost-effectiveness, and the ease of distribution and storage. Currently, plant systems, also referred to as biofactories, are being utilized for the expression of various proteins, which includes potential vaccines and pharmaceuticals, through employing several adaptations of recombinant processes and utilizing the most suitable tools and strategies. This is known as plant molecular farming. The level of protein expression is a critical factor in plant molecular farming, and this level fluctuates according to the plant species and the organs involved. The production of recombinant native and engineered proteins is a complicated procedure that requires an inter and multidisciplinary effort involving a wide variety of scientific and technological disciplines, ranging from basic biotechnology, biochemistry, and cell biology to advanced production systems. A lot of effort needs to be put in to achieve the desired goals.
