ABSTRACT

This chapter focuses on the analysis of a specific application area: the modeling of disease risk around a known location or locations. This focus is a particular example of a regression application which can have ecological elements. Some of the discussion will focus on case event level modeling, which is not at an aggregated level. In putative source analysis, the location(s) of potential source(s) of health hazard are known, and it is the task of the analysis to determine whether the source or sources affect health risk in their vicinity. Analyses will be formulated depending on whether a disease is of interest or whether a source is of potential interest. The evidence for the effect of the incinerator could be manifold. The primary effect might be elevated incidence near the site of the putative source. Hence one might be tempted to consider a distance decline effect around the source. This would be a primary form of evidence for a linkage.