ABSTRACT

Introduction ........................................................................................................ 233

Spray Drying ...................................................................................................... 235

Freeze Drying ..................................................................................................... 238

Storage of Dried Probiotic Powders ............................................................... 240

Applications of Dried Probiotic Powder Ingredients .................................. 240

Conclusions......................................................................................................... 242

Acknowledgments ............................................................................................. 242

References ........................................................................................................... 242

Probiotics, described as “live microorganisms which when consumed in

adequate amounts confer a health benefit on the host”(FAO/WHO, 2001),

are currently receiving much research attention, both from clinical and

commercial perspectives. Over the past two decades, the intake of probiotic

bacteria, particularly in dairy products, has increased substantially,

spawning an industry now valued at e30 billion worldwide (Saarela et al.,

2000; de Vos et al., 2004). The most commonly used probiotic strains for food

use belong to the genera Lactobacillus and Bifidobacterium (Stanton et al.,

2003), and generally share such features as generally recognized as safe

(GRAS) status of human origin and tolerance to acid and bile, in addition to

demonstrated health benefits (Ouwehand et al., 2002). A number of health

benefits have been demonstrated in clinical trials associated with

regular ingestion of probiotics, including alleviation of lactose intolerance

(Martini et al., 1991; Jiang et al., 1996), diarrhea (Isolauri et al., 1991; Saavedra

et al., 1994; Shornikova et al., 1997; Guandalini et al., 2000), atopic eczema

(Isolauri et al., 1999; Kalliomaki et al., 2001), and urinary tract infections

(Reid et al., 2003) (Table 13.1). While the clinical evidence for probiotics in

preventing and/or treating some disorders, particularly in the gut, are well

documented, there also appears to be potential for probiotics in areas such as

the management of inflammatory bowel diseases, Crohn’s disease, and

cancer, although further investigations are required (Shanahan, 2000;

Stanton et al., 2003).