ABSTRACT

References .....................................................................................................................................282

Linkage between exposure to particulate matter (PM) !10 mm in aerodynamic diameter (PM

)

and a number of acute and chronic health effects throughout the industrialized world has been well

established in epidemiological studies (e.g., [1-3]). Acute effects include mortality, hospitalization,

increased respiratory symptoms, decreased lung function, increased plasma viscosity, changes in

heart rate and heart rate variability (HRV), and pulmonary inflammation [4]. Chronic effects

associated with particulate exposures include increased mortality rates (e.g., cancer), chronic

cardiopulmonary disease, and decreased lung function [4]. Understanding the mechanisms

through which particulate exposures cause morbidity and mortality continues to be a critical

public health concern.