ABSTRACT
High-risk, potentially lethal ingestions: Aspirin, calcium channel blockers (CCBs) (especially verapamil), chloroquine, colchicine, cyanide, tricyclic antidepressants (TCAs). Recent ingestions, less than 1 to 2 hours, especially for slow-release drugs. Consequential toxicity: Seizures, hypotension, arrhythmias. Ineffective or nonexistent antidotes: CCBs, iron, colchicine, paraquat, selenious acid. Enteric-coated or slow, sustained-release tablets: Aspirin, theophylline, verapamil. Poisonings with agents that reduce gastrointestinal motility: Anticholinergics, opioids, sedative/hypnotics. Poisonings with agents that cause pylorospasm and gastric outlet obstruction: Aspirin, meprobamate, iron. Poisonings with agents that form gastric concretions or masses: Aspirin, enteric-coated and sustained-release tablets, iron, meprobamate, phenobarbital.
