ABSTRACT
Within the last decade, breakthroughs in genomic [1-4] and proteomic [5-10] methods have allowed a
plethora of disease-related biomarkers to be identified and validated. The discovery of these biomole-
cular targets provides new opportunities for the development of molecular diagnostics enabling earlier
and more accurate medical diagnoses through the detection of biomolecular analytes. High throughput,
sensitivity, and specificity are essential elements of useful diagnostic devices, and a great need remains
for technologies that fulfill these criteria.