Stability Assessment

Formulated pharmaceuticals are complex and often heterogeneous systems that

are difficult to analyze using standard analytical tools; this may be because the

object of the study is the active pharmaceutical ingredient (API), and any analysis

first requires its isolation from the rest of the medicine, or because the product

contains materials that are progressing through both chemical and physical

changes. In either case, isothermal calorimetry (IC) offers a potentially useful

alternative to conventional stability assessments because it simply monitors a

sample over time.