ABSTRACT

The preceding seven chapters have described the main principles of isothermal

calorimetry (IC) in the context of pharmaceuticals. Necessarily, such a discussion

can be predicated solely on currently available technology, and it should be clear

that calorimetric instrumentation lends itself to a wide variety of application

areas. However, instrumentation is constantly improving and often the develop-

ment of new technology opens new areas of application. It is the purpose of this

discourse to examine some of the potential areas of application for current calori-

metric technology and to consider some of the future technological developments

that might underpin the next generation of calorimetric instrumentation. In par-

ticular, attention will be paid to measurements made on whole systems, appli-

cations to processes scale up and process analytical technology (PAT), and the

development of high-throughput screening (HTS) methodologies.