ABSTRACT

References .......................................................................................................................... 568

Iontophoresis is a noninvasive technique in which a small electric current is applied to

enhance ionized drug penetration into tissue. The drug is applied with an electrode carrying

the same charge as the drug, and the ground electrode, which is of the opposite charge, is

placed elsewhere on the body to complete the circuit. The drug serves as a conductor of the

current through the tissue [1]. Figu re 26.1 shows a diagram of ocular iontophore sis of a

positively charged drug in a rabbit.