ABSTRACT
Interleukin-19, interleukin-20, and interleukin-24 belong to the interleukin-10 family of cytokines, which comprises a series of herpesviral and poxviral members and human cellular paralogs of IL-10 (IL-19, IL-20, IL-22, IL-24, and IL-26).1 Human cellular IL-10-related cytokines form additionally two subfamilies of more closely-related ligands based on receptor-chain sharing between these cytokines — IL-10 subfamily and IL-19 subfamily. The IL-10 subfamily contains IL-10 itself (see Chapter 10), IL-22, and IL-26 (see Chapter 12), while the IL-19 subfamily contains IL-19, IL-20, and IL-24 and is discussed in this chapter.2
