ABSTRACT

Introduction............................................................................................................156 Gaucher Phenotype(s)............................................................................................156 Role of Macrophage Activation and Inflammation in Development of Gaucher Disease ....................................................................................................157 Natural History ......................................................................................................158 Mode of Presentation of Type 1 Gaucher Disease ...............................................158 The Spleen in Gaucher Disease ............................................................................160 The Liver in Gaucher Disease...............................................................................160 Hematologic Manifestations..................................................................................161 The Bones in Gaucher Disease .............................................................................162