ABSTRACT
Inflammation by Spinal Adenosine Receptors ...........................................292 17.7 Potential Peripheral Mechanisms in the Inhibition
of Chronic Inflammation by Spinal Adenosine Receptors.........................293 17.8 Conclusions and Implications.....................................................................294 References..............................................................................................................295
Novel drug targets are being continually sought for the unmet medical needs associated with inflammatory diseases such as sepsis and rheumatoid arthritis. In the quest to identify naturally occurring substances that affect inflammation, the purine adenosine was discovered to have several properties that allow it to regulate inflammatory events, including inhibitory effects on neutrophil activation,
