ABSTRACT

Introduction............................................................................................................137 Evolutionary Aspects of Diet with Emphasis on Omega-6 and Omega-3 Essential Fatty Acids ........................................................................139 Biological Effects and Metabolic Functions of Omega-6 and Omega-3 Fatty Acids ........................................................................................................141 Clinical Intervention Studies and the Omega-6/Omega-3 EFA Balance .............146 Omega-3 Fatty Acids and Gene Expression .........................................................149 Diet-Gene Interactions: Genetic Variation and Omega-6 and Omega-3 Fatty Acid Intake in the Risk for Cardiovascular Disease ..............................152 Conclusions............................................................................................................153 References..............................................................................................................154