ABSTRACT
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Cell-penetrating peptides (CPPs) are accepted as a valuable tool in biological
research. However, several basic questions regarding the behavior of the CPPs
remain to be answered. What is clear is that the CPP phenomenon is universal: data
from our laboratory show that uptake occurs in several species of yeast and bacteria,
as well as insect cells and plant cells.1-3 Thus, the outer membrane of cells can vary
widely and still be permeable to CPPs.
