ABSTRACT
Acknowledgments ............................................................................................ 232
References ........................................................................................................ 232
Cells continuously export, import, and recycle molecules over the plasma membrane
by fundamental processes that can be capitalized upon for efficient intracellular
delivery of bioactive macromolecules, such as proteins and nucleic acids.
Proteoglycans emerge as key players in membrane transport, e.g., in the uptake of
polyamines, peptides, peptide-nucleic acid polyplexes, and microbes. This chapter
discusses proteoglycans in the context of endocytosis and CPP internalization.
