ABSTRACT
The Hansen solubility parameters (HSP) of many biological materials can be found from correlations of how they interact with well-defined liquids. The three HSP parameters,
δ
,
δ
, and
δ
quantitatively account for the cohesion energy density arising from atomic, dispersion type interactions (D), molecular, dipolar interactions (P), and molecular, hydrogen bonding interactions (H). Examples of HSP correlations included in this chapter are DNA, cholesterol, chlorophyll, wood chemicals, polypeptides (proteins), human skin, nicotine, lard, and urea. The often-quoted “like dissolves like” has been expanded to “like seeks like” (self-association) to discuss the implications of these correlations. The ability of HSP to correlate surface phenomena has made this change mandatory.
